What are Postbiotics?

What are Postbiotics?

What are Postbiotics?

Postbiotics are natural & functional bioactive compounds comprise of microbial-derived metabolites, ie, SCFAs & proteins that confer health benefits*.

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What are Postbiotics?

Postbiotics over 100 years in Japan

In Japan, postbiotics have been available for over 100 years**, and Professor Tomotari Mitsuoka*** pioneered in Japan in 1998 to only scientifically develop and study its health effects. (referred in Japan as Lactic Acid Bacteria (LAB, aka Probiotics) Metabolites or Lactobacillus Fermented Extracts)

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What are Postbiotics?

Postbioitics's direct effect

Postbiotics are now widely recognised as the primary source of health effect of probiotics^ and act on directly on host/human****.

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Graph Reference

The path towards microbiome-based metabolite treatment. Nature Microbiology 2, 17075 (2017)

What are Postbiotics?

Postbioitics: improving absorption for overall health

The recent studies suggest^ that Postbiotics effectively to suppress "bad" bacteria, promote native "good" bacteria growth for restoring gut flora balance and improving absorption disorders, which otherwise induces various health issues including:

  • Digestive discomfort (IBS, heartburn and diarrhoea, etc)
  • Obesity, blood sugar metabolism
  • Itchy and sensitive skin
  • Tiredness and poor sleep quality
  • Immune disorders
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References

  • *Role of Postbiotics in Diabetes Mellitus: Current Knowledge and Future Perspectives. Department of Health Science, Public University of Navarre, 31008 Pamplona, Spain. Foods 2021, 10, 1590.
  • **The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Gastroenterology & Hepatology Vol. 18 Sep 2021
  • *** Mitsuoka, T. Intestinal Flora and Probiotics (Gakkai Shuppan Center, 1998)
  • ^Postbiotics and their applications in early life nutrition and beyond. Int J Mol Sci. 2019; 20(19):4673
  • ****The path towards microbiome-based metabolite treatment. Nature Microbiology 2, 17075 (2017)